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WIRED June 3, 2020

Major Hydroxychloroquine Trial Shows No Prevention Benefits

by Adam Rogers

A large, double-blind study examined 821 people who had been exposed to the virus. The drug was no better at stopping Covid-19 infection than a placebo.

Read more at WIRED

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Research findings and data from the National Library of Medicine

PubMed articles

N Engl J Med JUNE 3, 2020

A Randomized Trial of Hydroxychloroquine as Postexposure Prophylaxis for Covid-19

DR Boulware et al

After high-risk or moderate-risk exposure to Covid-19, hydroxychloroquine did not prevent illness compatible with Covid-19 or confirmed infection when used as postexposur …

JAMA JUNE 23, 2020

Prescription Fill Patterns for Commonly Used Drugs During the COVID-19 Pandemic in the United States

M Vaduganathan et al

This pharmacoepidemiology study uses US pharmacy data to compare prescriptions for hydroxychloroquine/chloroquine and azithromycin in February to April 2020 vs 2019, and …

Lancet MAY 22, 2020

RETRACTED: Hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19: a multinational registry analysis

MR Mehra et al

William Harvey Distinguished Chair in Advanced Cardiovascular Medicine at Brigham and Women's Hospital.

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The Scientist OCTOBER 1, 2020

The Surgisphere Scandal: What Went Wrong?

The high-profile retractions of two COVID-19 studies stunned the scientific community earlier this year and prompted calls for reviews of how science is conducted, published, and acted upon. The warning signs had been there all along.

The New York Times JUNE 3, 2020

Malaria Drug Promoted by Trump Did Not Prevent Covid Infections, Study Finds

The first carefully controlled trial of hydroxychloroquine given to people exposed to the coronavirus did not show any benefit.

The Scientist MAY 27, 2020

WHO Halts Hydroxychloroquine Testing Over Safety Concerns

A paper published in The Lancet reported that hospitalized COVID-19 patients taking the drug had a higher risk of death, although some researchers have raised questions about the data.

WIRED JUNE 17, 2020

The FDA Revokes Its Emergency Use Authorization for Hydroxychloroquine

So far, no studies have shown that the antimalarial drug can fight Covid-19, and agency officials say its potential benefits do not outweigh its risks.

The Guardian MAY 22, 2020

Hydroxychloroquine: Trump's Covid-19 'cure' increases deaths, global study finds

Malaria drug should not be used to treat coronavirus, scientists say, after study shows high death rate