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News: Inexpensive Steroids Can Save Lives Of... (NPR News) - Behind the headlines

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NPR News September 2, 2020

Inexpensive Steroids Can Save Lives Of Seriously Ill COVID-19 Patients

by Richard Harris

Multiple studies now confirm earlier research: Dexamethasone and hydrocortisone, drugs that reduce an immune system's overreaction, can help reduce deaths of hospitalized COVID-19 patients.

Read more at NPR News

Behind the headlines

Research findings and data from the National Library of Medicine

PubMed articles

JAMA SEPTEMBER 2, 2020

Effect of Hydrocortisone on 21-Day Mortality or Respiratory Support Among Critically Ill Patients With COVID-19: A Randomized Clinical Trial

PF Dequin et al

In this study of critically ill patients with COVID-19 and acute respiratory failure, low-dose hydrocortisone, compared with placebo, did not significantly reduce treatme …

JAMA SEPTEMBER 2, 2020

Effect of Dexamethasone on Days Alive and Ventilator-Free in Patients With Moderate or Severe Acute Respiratory Distress Syndrome and COVID-19: The CoDEX Randomized Clinical Trial

BM Tomazini et al

Among patients with COVID-19 and moderate or severe ARDS, use of intravenous dexamethasone plus standard care compared with standard care alone resulted in a statisticall …

JAMA SEPTEMBER 2, 2020

Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial

Writing Committee for the REMAP-CAP Investigators et al

Among patients with severe COVID-19, treatment with a 7-day fixed-dose course of hydrocortisone or shock-dependent dosing of hydrocortisone, compared with no hydrocortiso …

Also of interest

Additional recent and related news

The Washington Post SEPTEMBER 2, 2020

Steroids can save lives of patients with severe covid-19, earning WHO endorsement

New studies confirm British findings and replicate them with multiple steroids.

The New York Times JUNE 16, 2020

Common Drug Reduces Coronavirus Deaths, Scientists Report

A steroid, dexamethasone, is the first drug shown to help save severely ill coronavirus patients, according to scientists in Britain.

The New York Times JANUARY 8, 2021

2 Arthritis Drugs Reduce Deaths in Very Ill Covid Patients, Study Finds

The big dip in mortality shown in the trial of about 800 patients has caught some experts by surprise because previous studies of the drugs showed little benefit.

BBC News JUNE 18, 2020

What is dexamethasone and how does it fight Covid-19?

A cheap steroid is hailed a big breakthrough in the treatment of seriously ill Covid-19 patients.

BBC News SEPTEMBER 2, 2020

Cheap steroids save lives from severe Covid

Eight lives would be saved for every 100 critically ill patients given steroids.